Glaucoma and other ocular complications in herpetic and HLA-B27 associated anterior uveitis.
Completed
- Conditions
- 10018307anterior uveitiseye inflammation
- Registration Number
- NL-OMON37375
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 101
Inclusion Criteria
Patients with anterior uveitis associated with herpes or HLA-B27.
Exclusion Criteria
Patients whose cause of anterior uveitis is not certain.
Patients having more than one cause for anterior uveitis.
Patients with other forms of uveitis than anterior uveitis.
Patients who were already diagnosed with elevated IOP or glaucoma before the occurrence of uveitis.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Primary outcome measures:<br /><br>• Intraocular pressure at presentation of first uveitis episode. (retrospective)<br /><br>• Intraocular pressure at the following uveitis episodes at first visit.<br /><br>(retrospective)<br /><br>• Course of intraocular pressure during treatment and control moment of<br /><br>uveitis.(retrospective)<br /><br>• Time of onset of glaucoma (after how many episodes / active duration).<br /><br>(retrospective)<br /><br>• Use of anti-glaucomatous agents. (Only treated during IOP elevation or also<br /><br>between IOP elevations. The total number of glaucoma medication used, is<br /><br>noted.) (retrospective)<br /><br>• Applied glaucoma surgery. (retrospective)<br /><br>• Use steroid eye drops. (retrospective / present status)<br /><br>• Current IOP, visual fields and optic disc status. (present status)<br /><br>• Duration of follow-up. (retrospective)</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary outcomes:<br /><br>• Secondary cataract (corticosteroid-induced). (retrospective / present status)<br /><br>• Formation of anterior synechiae and / or posterior synechiae. (present<br /><br>status)<br /><br>• Formation of cystoid macular edema. (retrospective / present status)<br /><br>• Visus (present status)<br /><br>• Slit lamp examination: presence of iris transillumination (radial, sector),<br /><br>pseudoexfoliation, Krukenberg's spindle. (present status)<br /><br>• Central corneal thickness (pachymetry) (retrospective / present status)<br /><br>• Glaucoma risk factors (family history, myopia, race) (present status)</p><br>