Evaluation of glaucoma or ocular hypertension patients with pre-existing ocular surface disease switched from a preserved prostaglandin analog – timolol fixed combination to a preservative – free latanoprost – timolol fixed combinatio
- Conditions
- Ocular HypertensionH40.1Primary open-angle glaucoma
- Registration Number
- DRKS00024581
- Lead Sponsor
- Department of Ophthalmology, University hospital center Zagreb
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 30
•Adult (?18years) patients
•With open angle galucoma or ocular hypertension that had been controlled (stable IOP <19mmHg) by commercially available preserved PGA –timolol FC for at least 3 months
•Stable visual field (based on at least two reliable visual field tests performed within the last 12 months)
•Central corneal thickness within the range 500-580µm.
•mild to moderate hyperaemia based on MacMonnies (scores 1 and 2)
•Best-corrected visual acuity (BCVA) 0,1 or lower
•Severe visual field defects (MD 12 dB or higher)
•Any intraocular surgery (other than filtration surgery performed at least 6 months before screening)
•Any ocular surface abnormality preventing accurate IOP measurement
•Acute ocular inflammation
•Contact lens wearers
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method