Compliance of Thyroid Fine Needle Aspiration Biopsy and Trucut Biopsy Results With TIRADS Score and Surgical Pathology

Completed

• Conditions: Thyroid Nodule
• Interventions: Procedure: Thyroid biopsy with ultrasound

• Registration Number: NCT04488640
• Lead Sponsor: Bezmialem Vakif University

Brief Summary

The investigators retrospectively reviewed the medical records of 760 patients with thyroid nodule biopsy and 88 patients who had thyroid surgery. The investigators evaluated patients' thyroid ultrasonography reports and determined Thyroid Imaging Reporting and Data System scores (TIRADS score: 1-Benign, 2- very low malignant) risk, 3-low risk, 4-medium risk, 5 -malignant high risk). The investigators evaluated patients 'existing thyroid fine needle aspiration biopsy (FNAB) reports and recorded the patients' cytology results (benign, malignant).

Documents of 88 patients who were included in the study and who underwent thyroidectomy were reviewed.Pathology reports of these patients were evaluated and surgical pathology was determined as benign in 58 patients and malignant in 30 patients.

Then, a statistical study was performed between the cor needle biopsy (CNB) results of these participants and the surgical pathology and TI-RADS scores.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-01-01
• Primary Completion: 2020-01-01
• Study Completion: 2020-05-01
• Status Verified: 2020-07
• Study First Submitted: 2020-07-15
• Study First Submitted QC: 2020-07-21
• Last Update Submitted: 2020-07-21
• Study First Posted: 2020-07-28
• Last Update Posted: 2020-07-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 4

Inclusion Criteria

• Having a thyroid nodule
• Being both a thyroid needle and a core biopsy

Exclusion Criteria

• Child patients
• Pregnant patients
• Patients without a thyroid needle biopsy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Thyroid core needle aspiration biopsy group	Thyroid biopsy with ultrasound	A patient group with 760 people who had a thyroid nodule and who had a thyroid fine needle aspiration biopsy for diagnosis and who underwent a core needle biopsy again. A total thyroidectomy was performed in 88 of these patients. Surgical pathology results, core needle results and TIRADS scores were compared.
Thyroid fine needle aspiration biopsy group	Thyroid biopsy with ultrasound	A group of 760 people who had a thyroid nodule and who had a thyroid fine needle aspiration biopsy for diagnosis.

Primary Outcome Measures

Name	Time	Method
Evaluation of the distribution of patients according to thyroid biopsy results.	4-year results were included.	Thyroid biopsy results (benign, malignant) will be compared with % of patients with these results. It will be analyzed statistically.
Examination of TIRADS score distribution according to thyroid biopsy results.	4-year results were included.	Thyroid biopsy results (benign, malignant) will be compared with the percentage of patients who fit the TIRADS score distribution (1-5). It will be analyzed statistically.
Evaluation of the compliance of TI-RADS scores with surgical pathology reports.	4-year results were included.	Surgical pathology results (benign, malignant) and TI-RADS scores (1 to 5) will be compared with% of patients matching the distribution (1-5). It will be analyzed statistically.
Evaluation of the distribution of thyroid biopsy results and surgical pathology results.	4-year results were included.	The % of patients who match the distribution of thyroid biopsy results (benign, malignant) and surgical pathology results (benign, malignant) will be compared. It will be analyzed statistically.