Implementation of a cost effective strategy to prevent neonatal infection by group B hemolytic streptococcus.

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 1260

Inclusion Criteria

Three Obstetric collaboration groups (OCGs) are recruited for this study. The study consists of a pre-test and a post- test. The pre-test is conducted for a period of three months and assesses adherence to the current Dutch guideline in prevention of neonatal GBS disease. After the pre-test the innovation strategy is applied in the three regions, to start with random allocation to a prevention strategy combined with implementation activities in the OCG. The actual introduction of the three prevention strategies will start in August 2013. To determine the effects of the implementation of the three strategies, a post-test is performed over a period of six months. During both the pre-test and post-test, all midwives and obstetricians will prospectively register all pregnant women from 30 weeks of gestational age onwards. All pregnant women will receive information about the EOGBS prevention strategy in their region and permission is acquired on the basis of opting out. Women who decline to participate will be treated in accordance with the current Dutch guideline.

Exclusion Criteria

Women who decline treatment according to the allocated strategy, will be treated in accordance with the current Dutch guideline.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Percentage of pregnant women that was offered the allocated prevention strategy;<br /><br>2. Percentage adherence to the allocated prevention strategy by care providers;<br /><br>3. Percentage adherence to the allocated prevention strategy by pregnant women.

Secondary Outcome Measures

Name	Time	Method
1. GBS colonisation of the baby;<br /><br>2. Length of hospital stay of the pregnant woman (in days);<br /><br>3. Length of hospital stay of baby (in days);<br /><br>4. Level of hospital care (standard, medium, high);<br /><br>5. Worries in pregnancy in general (Cambridge worry scale);<br /><br>6. Worries in pregnancy in GBS (based on Cambridge worry scale);<br /><br>7. Satisfaction with received care by parents during pregnancy, childbirth and first week after birth;<br /><br>8. Completeness of use of the prevention strategies by care providers.