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Clinical Trials/NCT05455905
NCT05455905
Completed
N/A

Voice Biomarkers Predictive of Depression and Anxiety: An Observational Study

Kintsugi Mindful Wellness, Inc.1 site in 1 country19,533 target enrollmentSeptember 14, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Depression, Anxiety
Sponsor
Kintsugi Mindful Wellness, Inc.
Enrollment
19533
Locations
1
Primary Endpoint
Hamilton Depression Rating Scale
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The objective of this study is to collect data to improve the sensitivity and specificity of Kintsugi Voice's (formerly KiVATM) predictions on audio files. A web-based audio recording tool will be used to record voice sample and ask participants the PHQ-9 and GAD-7 questions. A voluntary subset of participants will then be assessed by mental health professionals with the Hamilton Depression Rating Scale (HAM-D) and Hamilton Anxiety Rating Scale (HAM-A) scores.

Detailed Description

Participants will be recruited via various online mediums to participate in a voluntary observational study. Completing the consent and survey on their smart-phone, tablet, or computer, the participant will be asked to provide a 1-minute response to an audio prompt "How was your day?" After recording their response, the participant will be asked to complete the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 measures independently. In a second voluntary phase of the study, participants who indicated a score higher than 20, will be contacted by the research team via email to determine if they are interested in a voluntary follow-up to their initial study participation. Participants who would like to take part in the additional survey will complete additional voice recording responses to prompts and complete the Patient History Questionnaire and Generalized Anxiety Disorder-7. These participants will be contacted by a Mental Health Professional to discuss seeking mental health resources and clinicians, as well as, complete the Hamilton Depression Rating Scale and Hamilton Anxiety Rating Scale via the telephone.

Registry
clinicaltrials.gov
Start Date
September 14, 2021
End Date
September 11, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adult males and or females over the age of 18 at the time of informed consent. Adults with a known history of depression and/or anxiety and adults without a known history of depression and/or anxiety will be included in this study.
  • Access to a laptop, smart-phone or tablet with a functioning microphone
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • Fluency in English

Exclusion Criteria

  • Visual impairment that would make it difficult for the participant to see the web-based survey
  • Motor impairment that would make it difficult for the participant to use the web-based survey

Outcomes

Primary Outcomes

Hamilton Depression Rating Scale

Time Frame: Through study completion, on average 12months

Participants will be interviewed by mental health professionals using the clinically validated Hamilton Depression Rating Scale, which has a score range of 0 to 54, where higher scores are associated with higher severity of depression.

Hamilton Anxiety Rating Scale

Time Frame: Through study completion, on average 12 months

Participants will be interviewed by mental health professionals using the clinically validated Hamilton Anxiety Rating Scale, which has a score range of 0 to 56, where higher scores are associated with higher severity anxiety.

Study Sites (1)

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