Primary Liver Cancer Cohort of South China

Recruiting

• Conditions: Primary Liver Cancer

• Registration Number: NCT03297255
• Lead Sponsor: Huilian Zhu

Brief Summary

This longitudinal observational cohort study was designed to investigate factors that influencing the occurrence and long-term survival of patients with primary liver cancer. Basic informations and detailed diagnosis informations (AJCC/TNM stage, MELD score, Child-Pugh score, and BCLC stage) were collected by professional doctors. Clinical outcomes (death, recurrence, and metastasis) will be followed up every two years after therapy.

Detailed Description

Primary liver cancer (PLC) is highly malignant with high mortality which is particularly popular in China. Many factors are believed to associate with the occurrence and prognosis of liver cancer. This longitudinal observational cohort study was designed to investigate factors that influencing the occurrence and long-term survival of patients with primary liver cancer.

Study Timeline

• Study Start: 2013-01-01
• Status Verified: 2017-09
• Study First Submitted: 2017-09-25
• Study First Submitted QC: 2017-09-27
• Last Update Submitted: 2017-09-27
• Study First Posted: 2017-09-29
• Last Update Posted: 2017-09-29
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 4000

Inclusion Criteria

• age 18-80 years
• consistent with primary liver cancer diagnostic criteria
• first diagnosis (from diagnosis to admission interval of less than a month)
• did not do any treatment of liver cancer

Exclusion Criteria

• refused to participate in this study
• suffering from more than two kinds of primary tumors

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time of Death	Up to 10 years	The exact death time of each participants will be checked in the government medical records system

Secondary Outcome Measures

Name	Time	Method
Time of recurrence	From date of diagnosis until the date of cancer recurrence or date of death from any cause, whichever came first, assessed up to 10 years	Time of recurrence will be obtained by telephone interview or medical treatment records
Time of metastasis	From date of diagnosis until the date of cancer metastasis or date of death from any cause, whichever came first, assessed up to 10 years	Time of metastasis will be obtained by telephone interview or medical treatment records

Trial Locations

Locations (1)

Sun Yat-sen University Cancer Center; 🇨🇳 Guangzhou, Guangdong, China