Long-Term Outcomes of Different Surgical Techniques for Sacral Tarlov Cysts: A Prospective Cohort Study

Not yet recruiting

• Conditions: Sacral Tarlov Cysts; Symptomatic Sacral Cysts; Chronic Pain Related to Sacral Cysts; Neurological Dysfunction Associated With Tarlov Cysts

• Registration Number: NCT06756984
• Lead Sponsor: Beijing Jishuitan Hospital

Brief Summary

Brief Summary

The goal of this observational study is to evaluate the long-term outcomes of different surgical techniques for sacral Tarlov cysts in adult patients aged 18-75 years diagnosed with symptomatic sacral Tarlov cysts. The main questions it aims to answer are:

* Does one surgical technique result in better pain relief (measured by VAS score) and functional recovery (measured by JOA score) compared to others?

* How do different surgical techniques impact the long-term recurrence rate and complication rate?

Researchers will compare three surgical techniques:

1. Partial cyst wall resection with nerve root sleeve plasty.

2. Partial cyst wall resection with nerve root sleeve reinforcement and reconstruction.

3. Autologous fat/muscle with fibrin glue microscopic cyst filling.

Participants will:

* Undergo one of the three surgical procedures based on clinical indications.

* Complete preoperative and postoperative assessments, including pain and functional scoring, as well as MRI evaluations at baseline and during follow-up.

* Participate in a follow-up program for up to 2 years to monitor outcomes and recurrence.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-12-24
• Study First Submitted QC: 2024-12-24
• Study First Posted: 2025-01-03
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-12
• Study Start: 2025-05-13
• Last Update Posted: 2025-05-13
• Primary Completion: 2026-06-30
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain Reduction Assessed by Visual Analog Scale (VAS)	Baseline, 1 month, 3 months, 6 months, 12 months and 24 months postoperatively
Neurological Function Improvement Assessed by Japanese Orthopedic Association (JOA) Score	Baseline, 1 month, 3 months, 6 months, 12 months and 24 months postoperatively

Secondary Outcome Measures

Name	Time	Method
Recurrence Rate of Sacral Tarlov Cysts	12 months postoperatively and annually up to 2 years