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Substudy of lipid lowering trial on prevention of atherosclerosis in 75 or older on cholesterol absorption and synthesis

Not Applicable
Conditions
Hyper-LDL-cholesterolemia
Registration Number
JPRN-UMIN000002292
Lead Sponsor
International University of Health and Welfare
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
1000
Inclusion Criteria

Not provided

Exclusion Criteria

same as EWTOPIA75

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
0 to 24weeks (1)changes in cholesterol absorption and synthesis (2)changes in inflammation markers (3)changes in lipoproteins(RLPcholesterol, small dense LDL etc), oxydised phospholipid, oxdised cholesterol) (4)NT-proBNP
Secondary Outcome Measures
NameTimeMethod
relation to composite cardiovascular events (same as EWTOPIA75)
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