Effect of Acupuncture on Anti Mullerian Hormone and Assisted Reproduction Outcome in PCOS Patients Undergoing IVF

Not Applicable

Completed

• Conditions: PCOS
• Interventions: Device: Acupuncture(Hwato®)

• Registration Number: NCT01778621
• Lead Sponsor: Amina Altutunji

Brief Summary

Acupuncture at follicular phase of the cycle may improve the pregnancy rate. This study aims to compare assisted reproduction outcome between two groups of PCOS patients underwent IVF, one group received acupuncture and other group without acupuncture.

Detailed Description

Follicular phase acupuncture applied for PCOS patients underwent IVF to evaluate the effect of acupuncture on anti-mullerian hormone (AMH) and the effect on assisted reproduction outcome. It applied at certain acupoints according to the principles of traditional Chinese medicine.

Study Timeline

• Study Start: 2011-03
• Primary Completion: 2012-03
• Study Completion: 2012-05
• Study First Submitted: 2013-01-23
• Study First Submitted QC: 2013-01-25
• Study First Posted: 2013-01-29
• Status Verified: 2019-07
• Last Update Submitted: 2019-07-19
• Last Update Posted: 2019-07-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 102

Inclusion Criteria

:

• PCOS patients with patent one or two fallopian tubes, normal uterine cavity and partners with normal semen parameters.
• infertility
• 20-40 years
• IVF treatment -

Exclusion Criteria

• patients with disorders that have the similar clinical presentation
• closed both tubes
• abnormal semen parameters
• intracytoplasmic sperm injection (ICSI)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Acupuncture (Hwato®)	Acupuncture(Hwato®)	30-40 minutes acupuncture at certain acupoints that chosen according to traditional Chinese medicine and included LIV3,SP6,SP8,ST36,SP10,ST29,LI14,Ren 04;starting at follicular phase of the cycle till 2 days before oocyte picked up.

Primary Outcome Measures

Name	Time	Method
Clinical pregnancy rate.	13 months	Increase in pregnancy rate

Secondary Outcome Measures

Name	Time	Method
Ongoing pregnancy rate	15 months	Increase in ongoing pregnancy rate

Trial Locations

Locations (1)

Assisted Reproduction Center, Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; 🇨🇳 Wuhan, Hubei, China