Effect of acupuncture on clinical pregnancy rate in women undergoing IVF-ET
- Conditions
- In Vitro Fertilization-Embryo Transfer (IVF-ET)
- Registration Number
- ITMCTR2100004756
- Lead Sponsor
- Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- Not specified
1. Female, aged >= 20 and < 40 years;
2. IVF or ICSI, and fresh embryo transfer;
3. Controlled hyperstimulation (COH) using GnRH-A long regimen, GnRH-A short regimen or GnRH antagonist regimen;
4. 1-2 cleavage embryos or 1 blastocyst are to be transplanted;
5. Voluntarily signed the informed consent.
1. Previous implantation failure for more than 3 times;
2. Untreated uterine diseases that clearly affect the shape of the uterine cavity, including(uterine malformation, submucosal fibroids, adenomyosis, endometriosis, etc.).
3. Untreated endometritis, acute pelvic inflammation, mycotic vaginitis, bacterial vaginitis, adnexitis, hydrosalpinx, or other systemic infections;
4. Those who wish to undergo Preimplantation Genetic Diagnosis/ Screening (PGD/PGS) or donor embryo transfer;
5. Chronic diseases associated with adverse pregnancy outcomes, such as hypertension, clinically symptomatic heart disease, diabetes, liver disease, kidney disease, severe anemia, history of venous thrombosis, history of pulmonary embolism or cerebrovascular events, and malignant tumors;
6. Received Chinese medicine treatment aiming to regulate menstruation and promote pregnancy in recent one month, such as acupuncture, Chinese medicine decoction pieces or Chinese patent medicine.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical pregnancy rate;
- Secondary Outcome Measures
Name Time Method High quality embryo rate;The cleavage rate;Live birth rate;Fertilization rate;Embryo implantation rate;Anxiety score;Abortion rate;Number of retrieved oocytes;Cycle cancellation rate;Available embryo rate;