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Efficacy of Ayush medicine NOQ19 in treatment of COVID-19 patients

Completed
Conditions
Coronavirus as the cause of diseases classified elsewhere. Ayurveda Condition: COVID19,
Registration Number
CTRI/2022/01/039370
Lead Sponsor
Sriveda Sattva Private limited
Brief Summary

The current pandemic of Covid-19 has shaken the entire world. In spite of various scientific researches and technological advancements exact treatment to cure the disease is yet to be discovered. Ayurvedic medicine NOQ 19 is a polyherbal formulation that has immunomodulating and immune enhancing properties. The present randomized, double blind, placebo controlled, multi-centric trial is planned to determine the therapeutic efficacy of Ayurvedic medicine NF2 (NOQ19)  in treatment of symptomatic COVID-19 patients along with standard allopathic treatment.  GIMS providing COVID-19 Care will be involved in conducting this trial.  Admitted positive patients admitted in the hospital in the age group 18-65 years will be recruited and randomized into treatment and control arm.  Following randomization 50 of them will be given Ayurvedic medicine NAOQ19 along with standard treatment and other 50 will receive placebo plus standard treatment. The follow up period will be for maximum of 7 days. Outcome measures that will be assessed are time to become SARS CoV2 RT PCR negative, reduction in symptoms and duration of hospital stay. Apart from this the blood samples will be collected at entry and exit to measure CBC, KFT, LFT, serum CRP

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Hospitalized or in home isolation adult patient aged >18 years Confirmed COVID-19 infection (RT –PCR- Upper respiratory tract nasopharyngeal and oropharyngeal swab.
  • mild and moderate Symptomatic COVID 19 infection with or without comorbidities Willingness to participate in the study Indian nationals.
Exclusion Criteria

Age less than 18 years Pregnancy and Lactation Moribund state in which death is perceived to be imminent (≤48 hours) Patient not willing to participate in the study Participation in any other clinical study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To evaluate the effect of NF2 in COVID 19 patients as time to become COV2 RT-PCR negative, duration of hospital stay, time to resolution of symptoms7 days for each participant
Secondary Outcome Measures
NameTimeMethod
Effect of NF2 therapy on laboratory parameters - CBC, CRP, LFT, KFTEntry and Exit

Trial Locations

Locations (1)

Government Institute for Medical Science

🇮🇳

Nagar, UTTAR PRADESH, India

Government Institute for Medical Science
🇮🇳Nagar, UTTAR PRADESH, India
Dr Anurag Srivastava
Principal investigator
9415061563
dranurag23@gmail.com

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