A study to evaluate exposure to selected smoke constituents in healthy adult smokers using heated tobacco products for 5 days under clinical confinement - A study to evaluate exposure to selected smoke constituents in healthy adult smokers using heated tobacco products for 5 days under clinical confinement

On Day 5, significant reductions in most biomarkers of exposure (BoE) relative to the combustible cigarettes (CC) group were observed after switching to heated tobacco products. No changes in BoE were observed between baseline and Day 5 in the CC group. Significantly, the magnitude of the reduction in exposure to most of the selected harmful and potentially harmful constituents (HPHCs) observed in the heated tobacco product groups was close to that observed in the stopped smoking (SS) group.