Personalised nutritional advice to aid weight loss

Not Applicable

Completed

• Conditions: Abdominal obesity; Nutritional, Metabolic, Endocrine; Obesity

• Registration Number: ISRCTN46063864
• Lead Sponsor: Jagiellonian University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-12-03
• Study Completion: 2022-04-30
• Last Update Posted: 4 July 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 265

Inclusion Criteria

1. Aged between 18-65 years
2. Waist circumference >94 cm for men or >80 cm for women
3. BMI between 25-40 in kg/m2
4. Provided written informed consent

Exclusion Criteria

1. Diabetes
2. Severe hyperlipidemia
3. Other endocrine and metabolic diseases
4. Chronic inflammatory states
5. Diseases of the digestive or respiratory systems
6. Chronic kidney disease
7. Cardiovascular disease
8. Alcohol addiction
9. Pregnancy or lactation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Waist circumference will be measured at baseline and 4 months

Secondary Outcome Measures

Name	Time	Method
<br> 1. Classic clinical biomarkers measured using Enzyme-Linked Immunosorbent Assay (ELISA) at baseline and 4 months<br> 2. Metabolomics biomarkers measured using Nuclear Magnetic Resonance (NMR) and Liquid Chromatography-Mass Spectrometry (LC/MS) at baseline and 4 months<br> 3. Food intake biomarkers measured using Liquid Chromatography-Ion Mobility Spectrometry-Quadrupole Time of Flight Mass Spectrometry (LC-IMS-QToF MS) at baseline and 4 months<br> 4. Microbiome analysis in feaces using Next Generation Sequencing (NCS) at baseline and 4 months<br>