Efficacy of melatonin for postoperative pain relief and reduced blood loss after cesarean sectio

Phase 1

• Conditions: post partum haemorrhage i nPatients undergoing cesarean section; post-operative pain inPatients undergoing cesarean section; post partum haemorrhage i n; Patients undergoing cesarean section; post-operative pain in; Anaesthesiology - Anaesthetics; Reproductive Health and Childbirth - Fertility including in vitro fertilisation; Surgery - Other surgery

• Registration Number: ACTRN12612000117819
• Lead Sponsor: Qazvin Medical Science University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-01-24
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: 120

Inclusion Criteria

pregnant women at term (37—40 wks) gestation scheduled for either elective or emergency lower segment cesarean
section .

Exclusion Criteria

excluding criteria:Women with any risk factor
associated with an increased risk of postpartum
hemorrhage were excluded i.e. anemia (Hb8 g%), multiple gestation, antepartum hemorrhage,poly-hydramnios, two or more previous cesarean sections and/or a history of previous rupture uterus, current or previous history of significant disease including heart disease, liver, renal disorders or known coagulopathy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time to first requirement of analgesic supplement(analgesic administration was initiated by patient request(verbal rating scale[ VRS]>4)[Time to first requirement of analgesic supplement from the time of injection intrathecal anesthetic solution];amount of blood loss after cesarean delivery[amount of blood loss after cesarean delivery will be assess by determination of Hemoglobin values both before surgery and 12 h following surgery]

Secondary Outcome Measures

Name	Time	Method
hemodynamic variables 5min before the intrathecal injection,and at 2, 4, 6, 10, 15,20 min after the injection[hemodynamic variables is assessed by nonivasive automatic blood pressure measurement 5min before the intrathecal injection,and at 2, 4, 6, 10, 15,20 min after the injection]