To Assess The Efficacy Of Mercurius Solubilis Vis A Vis Constitutional Homeopathic Medicine In Management Of Halitosis: A Prospective Single Blind RCT
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- 1. To assess the improvement of halitosis by using Mercurius Solubilis.
研究概览
简要总结
This study is a randomized, single-blinded comparative clinical trial to study and prescribe medicines in cases of halitosis. The duration of treatment is 3 months and will be done on 52 patients at BVDUHMC, Pune. The results of patients will be assessed by using organoleptic scale and halimeter before and after treatment..
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- All
入选标准
- •Age between 18 to 40 years.
- •Diagnosed with Organoleptic scale and genuine halitosis based on clinical examination (sniff test) and halimeter.
- •Duration of symptoms more than one month.
- •Willing to provide written informed consent.
- •Available for the duration of study and follow-up.
排除标准
- •Pseudo-halitosis or halitophobia.
- •Halitosis due to known systemic diseases like uncontrolled diabetes, hepatic or renal failure.
- •History of recent dental procedures (within 1 month).
- •Use of antibiotics, antiseptic mouthwash, or probiotics within 2 weeks.
- •Known hypersensitivity to mercury compounds.
- •Pregnant and lactating women.
- •Mentally incapacitated individuals.
结局指标
主要结局
1. To assess the improvement of halitosis by using Mercurius Solubilis.
时间窗: Follow-up is taken after 14 days of the medicine prescribed.for the Period of 3 months. | The improvement in the follow up will be assessed based on the details of | Organoleptic scale and halimeter.(halimeter range -more than 200 ppb) | The second prescription will be based on the results of the follow up
2. To assess the effectiveness of constitutional homeopathic medicines in improving halitosis in cases that are not relieved by Mercurius Solubilis.
时间窗: Follow-up is taken after 14 days of the medicine prescribed.for the Period of 3 months. | The improvement in the follow up will be assessed based on the details of | Organoleptic scale and halimeter.(halimeter range -more than 200 ppb) | The second prescription will be based on the results of the follow up
3. To evaluate and compare the efficacy of Mercurius Solubilis and constitutional
时间窗: Follow-up is taken after 14 days of the medicine prescribed.for the Period of 3 months. | The improvement in the follow up will be assessed based on the details of | Organoleptic scale and halimeter.(halimeter range -more than 200 ppb) | The second prescription will be based on the results of the follow up
homoeopathic medicine in reducing the severity of halitosis in patients aged 18–40 years.
时间窗: Follow-up is taken after 14 days of the medicine prescribed.for the Period of 3 months. | The improvement in the follow up will be assessed based on the details of | Organoleptic scale and halimeter.(halimeter range -more than 200 ppb) | The second prescription will be based on the results of the follow up
次要结局
- 1.To reduce the social embarrassment caused to reduce the halitosis.(2. To assess the patient-reported symptoms using validated tools, such as organoleptic)
研究者
Dr Vaibhav Rathod
Bharati Vidyapeeth Deemed to be University Homoeopathic Medical College and Hospital