iver pre-conditioning by the portal vein embolization (PVE) before liver resection.

Recruiting

• Conditions: C22; Malignant neoplasm of liver and intrahepatic bile ducts

• Registration Number: DRKS00003723
• Lead Sponsor: Klinik für Allgemein-, Viszerall- und Transplantationsmedizin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-05-16
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

1. Patient is a male or female, obtaining a PVE during preoperative conditioning process
2. Patient is over 18 years of age
3. Patient provides written informed consent

Exclusion Criteria

1. Patient with a GFR < 30 ml/min/1,73 m2
2. Patient has or requires an implantable electronic defibrillator, pacemaker or other ferromagnetic implants
3. Patient with congenital long-QT-syndrom or corresponding family history
4. Patient has a known allergy to the contrast agent Primovist ®
5. Patient is treated with drugs prolonging the repolarization, e.g. Class III - anti arrhythmic agents (e.g. Amiodaron, Sotalol).
6. Patient has already underwent liver surgery (cholecystectomia is not a reason for exclusion
7. Any factors, decreasing the ability to apply and cooperate during the (e.g. mental dysfunction, claustrophobia or abuse of drugs)
8. Patient is pregnant or lactating

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Volume function analysis at the time points: before and after PVE as well as one, two, three and four weeks after PVE and after resection at days 1, 10 and 85.