Prophylactic effects of the homoeopathic medicine Eupatorium perfoliatum 30CH during the dengue outbreak in Kolkata: A comparative cohort study

Dengue is a major public health concern globally and a common cause of illness seen in primary care settings in tropical and subtropical countries. It is endemic in more than 100 countries in Africa, America, the Eastern Mediterranean, Southeast Asia, and the Western Pacific. This research on 1614 participants is aimed at contributing to the growing evidence base of prophylactic effects of the homeopathic medicine Eupatorium perfoliatum (EP) 30CH against dengue in Kolkata using a parallel cohort design. The primary objective of the study is to detect the group differences in the occurrence of confirmed dengue fever (DF) cases, while the secondary objective is to detect the group differences in the occurrence of probable DF cases and hospitalization. The homeopathic medication Eupatorium perfoliatum 30CH can be a promising preventive option for dengue, as evidenced by several preclinical and clinical findings. Effective dengue vaccines are yet to be developed and approved. In the meantime, this research may help reduce the occurrence of DF cases, thereby reducing the financial burden of the community. This work will add to the growing evidence base of the homeopathic medicine EP 30CH as a potent prophylactic for DF.