A Phase III Study of Intra-Arterial Hepatic Chemotherapy with 5-FU (WHF) in Patients with Liver Metastases from Colorectal Carcinoma
Phase 3
- Conditions
- iver excisionliver metastasis cancer of colorectal cancer origin
- Registration Number
- JPRN-C000000075
- Lead Sponsor
- Japanese Foundation for Multidisciplinary Treatment of Cancer
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 280
Inclusion Criteria
Not provided
Exclusion Criteria
1) active synchronous or metachronous malignancy other than carcinoma in situ 2) serious postoperative complications 3) serious coexisting illness a; diabetes mellitus, uncontrolled or controlled with insulin b; uncontrolled hypertension c; history of myocardial infarction, unstable angina within 6 months prior to the registration d; liver cirrhosis e; severe pulmonary dysfunction 4) pregnant or nursing 5) severe mental disorders 6) not suitable for participating in the study for any other reason
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method disease free survival
- Secondary Outcome Measures
Name Time Method survival, recurrence in residual liver, recurrence in extrahepatic lesion, adverse events