STUDY OF EFFECT OF ADDING DEXMEDETOMIDINE VERSUS CLONIDINE AS ADJUVANTS TO BUPIVACAINE IN ULTRASOUND GUIDED SUPRACLAVICULAR BLOCK

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/07/044197
• Lead Sponsor: Dr Niveditha B

Brief Summary

This is a Randomized, double blind study to evaluate and compare dexmeditomidine and clonidine for the onset and duration of sensory and motor blockade and duration of analgesia in elective upper limb surgeries. The pre-anaesthetic examination will be done and standard NPO guidelines will be followed.Tab Alprazolam 0.25mg will be given thenight before the day of surgery. In the pre-operative room ,patients baseline haemodynamic parameterswill be recorded and I.V access will be secured on opposite upper limb and crystalloidinfusion will be started and antacid prophylaxis of Inj.pantaprazole 40mg i.v, Inj. Ondansetron 4mgi.v will be given.After shifting the patient to the operation theatre andconnecting the monitors (NIBP, ECG , SPO2) , supraclavicular brachial plexusblock under ultrasound guidance will be carried out under strict asepticprecautions and patients will receive either of the study drug mentioned above.

The following parameters will be measured: Dermatomes of median nerve, radialnerve , ulnar and musculocutaneous nerve will be checked for sensory block, Sensory score2,Bromage scale6 for upper extremity on a 4 pointscaleMotor score. Haemodynamic variables will be recorded .The sensory and motor blockade willbe assessed and assessment of sedation will be done by Ramsay sedationscore.Post operative pain assessment will be done by10 point visual analog scale.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-07-19
• Study Start: 2022-07-25

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• 1.Patients willing to give written informed consent.
• 2.ASA physical status I and II patients.
• 4.Patients with Body Mass Index between 18 to 30 kg/m2.

Exclusion Criteria

• 1.Patients with pre-existing neurological disorder.
• 2.Patients with hypersensitivity to drug.
• 3.Inadequate block.
• 4.History of coagulopathy or anticoagulants treatment.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the onset and duration of sensory and motor blockade.	Sensory and Motor Blockade -3 minutes,6 minutes,9 minutes,12 minutes,15 minutes,18 minutes, 21 minutes,27 minutes and 30 minutes. | Sedation - 10 minutes,30 minutes, 60 minutes,120 minutes,240 minutes,360 minutes and 720 minutes.

Secondary Outcome Measures

Name	Time	Method
To evaluate haemodynamic variables	5 minutes, 10 minutes, 15 minutes, 20 minutes, 25 minutes, 30 minutes.

Trial Locations

Locations (1)

BGS Global Institute of Medical Sciences; 🇮🇳 Bangalore, KARNATAKA, India

BGS Global Institute of Medical Sciences

🇮🇳Bangalore, KARNATAKA, India

Dr Niveditha B

Principal investigator

9590377700

nivibasuraj94@gmail.com