Assistant to activate patients with dementia and their caregivers

Phase 2

• Conditions: F00; F01; Dementia in Alzheimer disease; Vascular dementia

• Registration Number: DRKS00013638
• Lead Sponsor: Ambulante Diakonische Dienste gGmbH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-02-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 53

Inclusion Criteria

1) type of dementia: Alzheimer’s disease or vascular dementia; diagnosed by professionals in memory clinic (CERAD neuropsychological battery); alternative for Siegen: Clinical Dementia Rating (CDR; Morris, 1993) value > 0.5
2) give consent
3) participants are retired
4) participants are mobile and able to stand up from a chair without support and walk 6m
5) care dependency measured by barthel index (BI): criteria: BI< 60 points (Mahoney & Barthel, 1965)
6) support by a professional caregiver or by an informal caregiver
7) written informed consent from patient with dementia and the informal caregiver
8) medical certification
9) cognitive and social requirements (interested, motivated, no aggressive behavior, can imitate exercises, understand simple verbal information, control of emotional reactions)
10) physical requirements (routine actions can be completed; also he/she can: see, hear, speak, sit and stand up, walk, grab and hold on a chair)
11) conditions of the environments (TV with HDMI, wireless internet at home)

Exclusion Criteria

1) other types of dementia (frontotemporal dementia, dementia with Lewy bodies, alcohol-relates brain damage (Korsakoff´s syndrome), familial Alzheimer's disease)
2) mental disorders like depression or generalized anxiety disorder who have not been satisfactorily medicated for at least six months; substance-related disorders in the last 2 years; schizophrenia and other psychological disorders
3) neurodegenerative diseases of the Central Nervous System (CNS), Parkinson’s disease, multiple sclerosis, Amyotrophic Lateral Sclerosis (ALS)
4) cardiovascular diseases: acute cardiac failure, acute cardiac insufficiency, angina pectoris, untreated cardiac arrhythmia or heart valve disease, pacemaker, untreated hypertension - systolic blood pressure >180 mm Hg or diastolic blood pressure > 110 mm Hg; untreated hypotension - < 90/60 mm Hg
5) untreated cancer disease
6) untreated hormone diseases
7) badly controlled diabetes (blood glucose < 6 mmol/L or >15 mmol/L)
8) epilepsy
9) Chronic Obstructive Pulmonary Disease (COPD) grade 4
10) acute infection or fever
11) acute renal insufficiency
12) osteoporosis
13) surgical interventions in the last 6 months
14) taking neuroleptics or benzodiazepine
15) participation in another study for dementia

Study & Design

• Study Type: interventional
• Study Design: Not specified