The effect of cognitive load on neural responses to sweet and sour tastes

Completed

• Conditions: normaal functioneren van smaakverwerking in de hersenen; healthy participants are included to examine taste processing

• Registration Number: NL-OMON49118
• Lead Sponsor: niversiteit Leiden

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-09-17
• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 64

Inclusion Criteria

• Healthy (self-reported)
• Right-handed
• Between 18 and 45 years old.
• Having given their written informed consent
• BMI between 18.5-30 kg/m2

Exclusion Criteria

• Having a history of or current alcohol consumption > 28 units per week
• Daily smoking
• Suffering from cold symptoms
• Having a history of medical or surgical events that may significantly affect
the study
outcome, such as metabolic or endocrine disease, or any gastro-intestinal
disorder
• Mental or physical status that is incompatible with the proper conduct of the
study
• Not having a general practitioner
• Participation in any other clinical trial during this study.
• Common MRI exclusion criteria, including
o Claustrophobia
o Presence of metal in body incompatible with MRI scanning
o Pacemaker
o Being pregnant.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Neural activation as measured by fMRI and perceived taste intensity and hedonic<br /><br>value in response to tasting sweet and sour solutions under high and low<br /><br>cognitive load. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Performance on the Stroop task (to measure attentional control), BMI, responses<br /><br>on the mobile Approach-Avoidance task (AAT) to measure food approach motivation</p><br>