Women With Migraine With Aura Neuroimaging Study
Completed
- Conditions
- Migraine With Aura
- Registration Number
- NCT02047695
- Lead Sponsor
- Odense University Hospital
- Brief Summary
The purpose of this study is to investigate whether a particular form of migraine, migraine with aura, is associated with structural changes in the brain
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 345
Inclusion Criteria
- female
- case (migraine with aura), co-twin to case, or control (migraine-free)
- residency in Denmark
- no severe neurological (vascular, neurodegenerative or neuroinflammatory) disorders, or other somatic or psychiatric disorders
Read More
Exclusion Criteria
- male
- residency outside Denmark
- registered in Civil Registry as not to be contacted by researchers
- severe neurological (vascular, neurodegenerative or neuroinflammatory) disorders, or other somatic or psychiatric disorders
- mobile metal parts or other contraindication for MRI
- weight of 130+ kilograms
- pregnancy
- subjects that wished not to be informed about abnormal findings on MRI
- chronic tension-type headache, medication overuse headache, or cluster headache (diagnosed through physician interview)
- frequent tension-type headache (control group only, self-reported or diagnosed through physician interview)
Read More
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evidence of white matter hyperintensities or subclinical ischaemic stroke confirmed by MRI At time of MRI
- Secondary Outcome Measures
Name Time Method Evidence of other structural and functional changes in brain At time of MRI