XGBoost for Predict Incisional Hernia

Recruiting

• Conditions: Incisional Hernia
• Interventions: Diagnostic Test: Not intervention

• Registration Number: NCT05718999
• Lead Sponsor: Hospital Regional de Alta Especialidad del Bajio

Brief Summary

The objective of this study is to develop a predictive model of IH based on machine learning with the use of the XGBoost technique, this will help surgeons in charge of abdominal wall closure to have objective support to determine high-risk patients and in them modify the closure technique or use a mesh according to their choice or the degree of contamination of the abdominal cavity.

Detailed Description

Retrospective and observational study. The predictions will make using machine learning models. The programs use the scikit-learn, xgboost and catboost Python packages for modeling.

The evaluation of models will be using fourfold cross-validation, the receiver operating characteristic (ROC) curve, the area under the ROC curve (AUC), and accuracy metrics calculated on the union of the test sets of the cross-validation.

The most critical factors and their contribution to the prediction will identify using a modern tool of explainable artificial intelligence called SHapley Additive exPlanations (SHAP).

Study Timeline

• Study Start: 2023-01-30
• Study First Submitted: 2023-01-30
• Status Verified: 2023-02
• Study First Submitted QC: 2023-02-07
• Study First Posted: 2023-02-08
• Primary Completion: 2023-02-22
• Last Update Submitted: 2023-02-23
• Last Update Posted: 2023-02-27
• Study Completion: 2023-11-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Patients older than 18 years of age
• Postoperative midline exploratory laparotomy, who underwent urgent or scheduled surgery, regardless of their underlying diagnosis,
• included between January 2010 and December 2016 and who completed 24 months of follow-up after surgery initial surgery.

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Exclusion Criteria

• Reoperated for any cuestion diferent to present of hernia
• Management of open abdomen

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
With Incisional Hernia	Not intervention	The incisional hernia was defined according to the EHS guidelines as a mass in the abdominal wall with or without a visceral outlet or palpable in the surgical site determined by clinical examination or tomography, this group will present this complication.
Without Incisional Hernia	Not intervention	The incisional hernia was defined according to the EHS guidelines as a mass in the abdominal wall with or without a visceral outlet or palpable in the surgical site determined by clinical examination or tomography, this group will not present this complication.

Primary Outcome Measures

Name	Time	Method
Incisional Hernia	24 months	incidence of Incisional hernia (the incisional hernia was defined according to the EHS guidelines as: a mass in the abdominal wall with or without visceral outlet or palpable in the surgical site determined by clinical examination or tomography).

Secondary Outcome Measures

Name	Time	Method
Facial dehiscence	30 days	Incidence of fascial dehiscence (the fascial dehiscence is the presentation of separation of fascie with leakage of contents from the abdominal cavity

Trial Locations

Locations (1)

Hospital regional de Alta Especialidad del bajio; 🇲🇽 Leon, Guanajuato, Mexico