Comparative study of laser treatments for intraocular pressure control in patients with glaucoma
- Conditions
- GlaucomaA01.456.505.420
- Registration Number
- RBR-4h3xvg5
- Lead Sponsor
- RR Clínica Oftalmológica Ltda
- Brief Summary
Results: In total of 98 followed POAG patients, 52 individuals were included SLT group and 46 in MLT group. Absolute and percentage of IOP decrease from baseline demonstrated that laser treatment, in both groups, resulted in significant and similar average IOP decrease from baseline in all studied periods (ANOVA, p<0.001). At 12 months, mean IOP decrease from baseline was greater with SLT compared to MLT group, -6.0 + 3.3 mmHg (24.9%) and -5.8 + 2.6 mmHg (23.4%) respectively, however not statistically significant (p=0.74). Laser treatment success was observed in 32 (61.5%) of SLT cases compared to 27 (58.7%) of MLT patients (p=1.0), at 12 months. A Kaplan-Meier curve of laser success in both groups showed similar survival steps at all intervals (P-value of 0.629). At 12 months, 55.6% of SLT cases, considered laser successes, required less medication as compared to MLT group successes (13.5%) (p 0.02).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Primary Open Agle Patients on medical treatment (drops) in need to adjunctive intra-ocular pressure treatment to reach target pressure
Glaucoma patients with clinical diagnosis other than Primary Open Angle Glaucoma; advanced visual field defects; patients who had already undergone laser or fistulizing surgery for glaucoma control; history of ocular surgery within 6 months or prior laser to treatment or during 12-month follow-up period after the procedure; history of trauma and concurrent use of systemic or topical steroids and patients with corneal conditions precluding adequate laser treatment. In cases where both eyes were eligible we included only eye with higher baseline intraocular pressure
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method