Randomized controlled clinical study to evaluate the efficacy of Ervarubijadi Yoga in the management of Pittaj Mutrakrucchra in children with special reference to lower urinary tract infection.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Dysuria,Burning Micturition,Frequent Urination
研究概览
简要总结
According to Ayurveda Mutrakricchra is a disease of Mutravaha Strotas. Mutrakrucchra is a broad term which covers the conditions described in modern medical science as Urinary Tract Infection (UTI). The Pratyatma Lakshana of Mutrakrucchra is “Dukhena Mutra Pravrutti†means discomfort during micturition. In Pittaj Mutrakrucchra, the vitiated pitta dosha along with vata (mainly Apana Vayu) on reaching basti afflicts the Mutravaha Strotas.
Mutrakrucchra is also found as a lakshana in many diseases such as Ashmari, Mutraghata, Mutrajvriddhi, Arsha and Gulma*.*
The Lakshana of Mutrakrucchra in children is described by Acharya Kashyap in Vedana adhyay.
RATIONALE OF STUDY
Urinary tract is the third commonest site of infection in children after gut and respiratory tract, involving lower urinary tract (cystitis, urethrits) or upper urinary tract infection (pyelonephritis) or both. About 2-8% of children develop UTI by the age of 14 years
About 1-3% boys and 3-8% girls suffer with at least one attack of symptomatic UTI by 14yrs of age. They are an important cause of morbidity and might result in renal damage often in association with vesicoureteric reflux. Dysuria is one among the important symptoms of the lower UTI by which the patient’s daily activities are hampered. With the introduction of effective antibiotics, problem has been solved to some extent but the use of antibiotics have side effects, chances of re-infection and relapse even after long term therapy. Simultaneously increasing incidence of resistance and high cost of therapy are common problems. So, there is a need to find low cost, harmless and preventive drug prepared from natural resources in the management of mutrakrucchra.
Acharya Charak has mentioned Ervarubijadi Yoga for the treatment of mutrakrucchra in children which consists of Ervaru, Yashtimadhu and Devadaru.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 6.00 Day(s) 至 16.00 Day(s)（—）
- 性别
- All
入选标准
- •Children of age group 6 years-16 years.
- •Patients irrespective of gender, caste, socioeconomic status.
- •Patients with classical signs and symptoms of pittaj mutrakrucchra sadah, saruja, muhurmuhu mutrapravritti etc.
- •Only those patients will be selected whose parents are willing to give written consent.
排除标准
- •Patients below 6 years and above 16 years.
- •All other types of Mutrakrucchra except Pittaj.
- •Patients with congenital abnormalities and other systemic diseases.
结局指标
主要结局
Dysuria,Burning Micturition,Frequent Urination
时间窗: Baseline 1st, 4th and 7th day
次要结局
- No. of pus cells, no. of RBCs, pH OF urine(Baseline 1st, 4th, 7th day)
研究者
Ankita Ramkrushna Bobade
Chhatrapati Shahu Maharaj Shikshan Sanstha Ayurved Mahavidyalaya, Aurangabad