CTRI/2025/12/099350尚未招募不适用
A STUDY TO EVALUATE THE EFFECT OF REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (rTMS) FOR TREATMENT OF DEPRESSION IN PERSONS WITH PARKINSON’S DISEASE
Dr Nandini Sharma1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年12月31日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
研究概览
简要总结
This study titled as a study to evaluate the effect of repetitive transcranial magnetic stimulation for treatment of depression in persons with parkinsons disease is an inetrventional study to assess the efficacy of high frequency rTMS over left dorsolateral pre frontal cortex in depression in persons with parkinsons’s disease. Eligible participants will undergo 10 sessions of high frequency rTMS over left DLPFC and will be assessed using HAMD, WHOQOL-BREF and MOCA to assess depressive symptoms, overall quality of life and cognitive functions at baseline 2 weeks and 4 weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 45.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •Participants diagnosed with parkinsons disease, scoreing more than 8 on HAMD and treatment non response with at least 1 antidepressant.
排除标准
- •Any comorbid active psychiatric disorder, implanted metal device in brain head cardiac pacemaker or prosthesis in inner ear, pregnant and active breastfeeding females, history of neuromodulation in past three months.
- •history of psychosurgery, dementia with MOCA score of less than 24, known seizure disorder or brain tumour.
研究者
Dr Nandini Sharma
ABVIMS & DR. RML Hospital New Delhi
研究点 (1)
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