Study about adult female acne and modification after treatment

Not Applicable

Recruiting

• Conditions: acne

• Registration Number: RBR-10cj37zj
• Lead Sponsor: niversidade Federal de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-10-10
• Last Update Posted: 29 May 2023
• Study Completion: 2023-06-30

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women aged between 25 and 44yo; presence of moderate facial acne (11 to 20 lesions); with or without scarring and sequels of hyperpigmentation; with no other signs or symptoms of hyperandrogenism; after informed consent and photographic consent signature.

Exclusion Criteria

pregnant or lactating; light or severe acne; treatment of acne with oral cyclin group antibiotics (previous three months); oral isotretinoin (previous six months); topical products (previous three months, except cleansers, moisturizer and sunscreen); oral spironolactone at any time; combined oral contraceptive started in the last 6 months; other drugs: cortisone, lithium, anticonvulsants, isoniazid, androgens, danazol, iodides, bromides, disulphide, cyclosporine, azathioprine, thiourea, vitamins B2, B6 and B12; contraindications to the treatment options - for spironolactone: use of aldosterone antagonist (amiloride or eplerenone); renal insufficiency; hyperkalaemia; Addison’s disease; significant low blood pressure; hypersensivity to spironolactone; for AA: previous allergic or irritative symptoms to AA.

Study & Design

• Study Type: Intervention
• Study Design: Not specified