Role of inflammation in skin barrier function and disease severity in children with atopic dermatitis
Not Applicable
- Conditions
- Health Condition 1: L209- Atopic dermatitis, unspecified
- Registration Number
- CTRI/2019/09/021215
- Lead Sponsor
- IADV
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Atopic Dermatitis (Moderate to Severe: SCORAD >25)
Exclusion Criteria
Children receiving systemic immunosuppressive therapy in last 1 month
Children with serious systemic illness
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation between Th2/Th17 inflammatory cytokines to epidermal filaggrin expression in children with moderate atopic dermatitis with or without underlying filaggrin mutationTimepoint: Baseline
- Secondary Outcome Measures
Name Time Method Correlating the epidermal filaggrin expression to score for atopic dermatitis (SCORAD) and transepidermal water loss (TEWL) in children with atopic dermatitis <br/ ><br>Correlating the levels of Th2/Th17 inflammatory cytokines to score for atopic dermatitis (SCORAD) and transepidermal water loss (TEWL) in children with atopic dermatitisTimepoint: Baseline