IL-7 and IL-2 dependent T cell response in pediatric type 1 diabetes

Recruiting

• Conditions: E10; Type 1 diabetes mellitus

• Registration Number: DRKS00007397
• Lead Sponsor: niversitätklinikum Düsseldorf Klinik für Allgemeine Pädiatrie, Kinderkardiologie und Neonatologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-11-11
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

type 1 diabetes; at manifestation or with diabetes duration of at least one year; age 0-18

Exclusion Criteria

acute infection

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Differences in the T cell response depending on age at manifestation, duration of diabetes, metabolic parameters.<br><br>What: T cell response, isolation of micro RNA, data from the patient's health record, metabolic parameters<br><br>When: one study appointment (arm 3 and 4), two study appointments (arm 1 and 2); second visit 6 to 12 weeks after first visit<br><br>How: Flow cytometry

Secondary Outcome Measures

Name	Time	Method
Differences in the T cell response depending on clinical parameters.<br><br>What: T cell response, isolation of micro RNA, data from the patient's health record, metabolic parameters<br><br>When: one study appointment (arm 3 and 4), two study appointments (arm 1 and 2)<br><br>How: Flow cytometry