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Study of serum interleukin 17 level in children with bronchial asthma

Not Applicable
Conditions
Respiratory
Paediatrics
Registration Number
PACTR201602001487159
Lead Sponsor
mohammed sami bazzari
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
85
Inclusion Criteria

Every Asthmatic child had at least three attacks of (paroxysmal dyspnea, cough, and wheeze).
Attack was relived spontaneously or with treatment (mainly with beta 2 agonist).
Patients had to be completely symptoms free for at least 2 weeks in between attacks.
Asthmatic children had to fulfill the criteria of asthmatic diagnosis of GINA guidelines (2014) [6].

Exclusion Criteria

Any patient had been used systemic corticosteroid in order not to affect Interleukin 17 serum level.
Patients were diagnosed with any of Asthma differential diagnoses diseases
Patients were known as a carrier of a blood transmitted infectious disease or had suffered from conditions in which phlebotomy was contraindicated.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
There was a highly significant difference in serum levels of IL-17 and total IgE in asthmatic than in control groups in children.
Secondary Outcome Measures
NameTimeMethod
There was also insignificant positive correlation between IL-17and IgE
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