Clinical Trial of Two Study Drinks in Detoxification of Environmental Toxicants and Carcinogens
Phase 2
Completed
- Conditions
- Healthy
- Registration Number
- NCT03978117
- Lead Sponsor
- Masonic Cancer Center, University of Minnesota
- Brief Summary
The goal of this research is to determine if consuming one of two study drinks will help enhance the detoxification of multiple environmental toxicants and cancer causing agents, particularly in subjects who are null for glutathione-S-transferase M1 (GSTM1), glutathione-S-transferase T1 (GSTT1), or both. If our research supports this idea, this drink could be an inexpensive dietary component, which could promote good health.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 305
Inclusion Criteria
- Adult Male or female. Participants can be smokers or non-smokers
- In good physical health
- In stable and good mental health
- Not using any medications that may affect the Nrf2 pathway
- Women who are not pregnant or nursing or planning to become pregnant
- Participants have provided written informed consent to participate in the study
Exclusion Criteria
- Significant immune system disorders, respiratory diseases, kidney or liver diseases or any other medical disorders that may affect biomarker data as determined by the licensed medical professional
- Vital signs outside of the allotted range
- Not willing to abstain from eating cruciferous vegetables during the course of the study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Effect of study drink Preparation on toxins 2 Months Prevalence of environment toxins in study population
Effect of study drink Preparation on carcinogens 2 Months Prevalence of carcinogens in study population
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Minnesota
🇺🇸Minneapolis, Minnesota, United States
University of Minnesota🇺🇸Minneapolis, Minnesota, United States