Randomized Controlled Trial of a Water Beverage Intervention for Promoting Modest Weight Reduction in Free Living Adults

University of North Carolina, Chapel Hill1 个研究点分布在 1 个国家目标入组 318 人2008年3月

适应症Obesity

概览

阶段: 不适用
干预措施: 未指定
疾病 / 适应症: Obesity
发起方: University of North Carolina, Chapel Hill
入组人数: 318
试验地点: 1
主要终点: Weight change
状态: 已完成
最后更新: 14年前

概览研究者入排标准结局指标研究点相似试验

概览

简要总结

The primary objectives of this clinical trial are to determine if replacing sugar sweetened beverages with water consumption promote weight loss over 6 months in overweight adults and if replacing sugar sweetened beverages with water consumption promote greater weight loss over 6 months relative to replacement with other non-caloric sweetened beverages or control.

The secondary objective is to identify mediators and moderators of the effect of water replacement including hydration status, glucose metabolism, anthropometrics, physical activity, dietary intake and resting metabolic rate.

注册库

clinicaltrials.gov

开始日期

2008年3月

结束日期

2010年1月

最后更新

14年前

研究类型

Interventional

研究设计

Parallel

性别

All

研究者

发起方

University of North Carolina, Chapel Hill

入排标准

入选标准

•18-65 years of age.
•Body mass index (BMI) between 25.0-49.9 kg/m
•Subject consumes at least 280 calories per day from caloric beverages.

排除标准

•Report losing \>5% of current body weight in the previous 6 months.
•Report participating in a research project involving weight loss or physical activity in the previous 6 months, as these proximal experiences may impact the results of this study. Additionally, report current participating in any other research studies whose results could be compromised by or in which participation could compromise this research study. (Participation in a research study that would not affect or be affected by this study is allowed.)
•Report pregnancy or lactation during the previous 6 months, or planned pregnancy in the next 6 months.
•Report taking medication that could affect metabolism or change body weight (e.g., synthroid).
•Report hospitalization for psychiatric problems during the prior year.
•Report major psychiatric diagnoses and organic brain syndromes.
•Report heart problems, chest pain, cancer within the last 5 years
•Being treated by a therapist for psychological issues or problems with psychotropic medications.
•Report behaviors that indicate probable alcohol dependence as assessed by the Rapid Alcohol Problems Screen (RAPS4-QF) (Cherpitel CJ, 2002).
•Unwilling to change intake of beverages during the study period.