An open-label study on the efficacy and safety of subcutaneous adipose tissue-derived cell aggregates (S-ADSCs) transplantation using an adhesive cell culture plate for knee osteoarthritis - OL-ES-S-ADSCs-KOA

Sobajima Satoshi0 个研究点目标入组 10 人开始时间: 2023年1月5日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•Patients with dysfunction associated with osteoarthritis
•-Over 20 years old when obtaining consent
•-Diagnosed with osteoarthritis of the knee at our hospital, and there is no improvement even after implementing standard conservative therapy (hyaluronic acid injection and physical therapy) that is fully covered by insurance for more than 3 months.
•-After standard conservative therapy for 3 months or more, pain evaluation value of 40 or more by visual analogue scale
•-Don't wish to perform artificial joint replacement or osteotomy
•-Obtain written consent sufficient explanation about this study
•-Able to comply with a fixed schedule

•-Patients who have difficulty in subcutaneous liposuction
•-Patients with cancer
•-Pregnant women, lactating women and patients who may become pregnant
•-Patients using anticancer drugs, biopharmacy or immunosuppressive drugs
•-Patients with active infection
•-Patients who have received intra-articular transplantation of S-ADSCs in the past
•-Patients who have received this treatment within 1 month
•-Patients with serious complications (heart disease, lung disease, liver disease, renal disease, bleeding tendency, uncontrolled diabetes and hypertension, etc.) that the doctor deems inappropriate
•-Patients with a history of drug hypersensitivity to anesthetics, etc.
•-Other patients who the attending physician deems inappropriate

发起方

Sobajima Satoshi