Evaluation of Protein Requirements in Active Adolescent Males
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Healthy
- Sponsor
- University of Toronto
- Enrollment
- 7
- Locations
- 1
- Primary Endpoint
- 13CO2 ([13]Carbon Dioxide) Excretion (µmol/kg/h)
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Protein requirements in active individuals have been suggested to be greater than the current recommended dietary allowance (RDA).
Nutritional requirements for dietary amino acids in adolescents have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity.
Recent studies using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 50% higher than the RDA based on nitrogen balance data.
The purpose of this study is to measure the protein requirement in adolescent, males using the IAAO technique in the presence of a variable intensity exercise stimulus.
Investigators
Daniel Moore
Assistant Professor
University of Toronto
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
13CO2 ([13]Carbon Dioxide) Excretion (µmol/kg/h)
Time Frame: 4 hours per study day
Each trial day will assess a different protein intake with 13CO2 excretion defining the level of protein adequacy. Each trial day will be separated by \~1wk washout with all trial being completed in approximately 3 months.
Secondary Outcomes
- [13C]Phenylalanine Oxidation (µmol/kg/h)(4 hours per study day)