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临床试验/NCT02626429
NCT02626429已完成不适用

Evaluation of Protein Requirements in Active, Young Adult Females

University of Toronto0 个研究点目标入组 6 人开始时间: 2015年5月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
6
主要终点
13CO2 (carbon dioxide) excretion (μmol/kg/h)

研究概览

简要总结

Protein requirements in active individuals have been suggested to be greater than the current recommended dietary allowance (RDA).

Nutritional requirements for dietary amino acids in adults have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity.

Recent studies using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 50% higher than the RDA based on nitrogen balance data.

The purpose of this study is to measure the protein requirement in active, young adult females using the IAAO technique in the presence of a variable intensity exercise stimulus.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Healthy, active, young adult females who regularly participate in moderate-vigorous activity 5x per week, for a minimum of 1 hour
  • A minimum score of 10 on the Beep Test (a measure of aerobic fitness)

排除标准

  • Inability to meet health and physical activity guidelines according to the physical activity readiness questionnaire (PAR-Q+)
  • Inability to adhere to any of the protocol guidelines (i.e. alcohol, caffeine consumption)
  • Regular tobacco use
  • Illicit drug use

研究组 & 干预措施

Active, Young Adult Famale

Experimental

Participants will complete a bout of exercise and then consume a randomly assigned amino acid intake prior to measuring whole body 13CO2 excretion and phenylalanine oxidation.

干预措施: Amino acid intake (Dietary Supplement)

结局指标

主要结局

13CO2 (carbon dioxide) excretion (μmol/kg/h)

时间窗: 4 hours / study day

次要结局

  • 13C-Phenylalanine Oxidation (μmol/kg/h)(4 hours / study day)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Daniel Moore

Assistant professaor

University of Toronto

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