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Clinical Trials/NCT02626429
NCT02626429
Completed
Not Applicable

Evaluation of Protein Requirements in Active, Young Adult Females

University of Toronto0 sites6 target enrollmentMay 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Increased Metabolic Requirement
Sponsor
University of Toronto
Enrollment
6
Primary Endpoint
13CO2 (carbon dioxide) excretion (μmol/kg/h)
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

Protein requirements in active individuals have been suggested to be greater than the current recommended dietary allowance (RDA).

Nutritional requirements for dietary amino acids in adults have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity.

Recent studies using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 50% higher than the RDA based on nitrogen balance data.

The purpose of this study is to measure the protein requirement in active, young adult females using the IAAO technique in the presence of a variable intensity exercise stimulus.

Registry
clinicaltrials.gov
Start Date
May 2015
End Date
June 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Single Group
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Daniel Moore

Assistant professaor

University of Toronto

Eligibility Criteria

Inclusion Criteria

  • Healthy, active, young adult females who regularly participate in moderate-vigorous activity 5x per week, for a minimum of 1 hour
  • A minimum score of 10 on the Beep Test (a measure of aerobic fitness)

Exclusion Criteria

  • Inability to meet health and physical activity guidelines according to the physical activity readiness questionnaire (PAR-Q+)
  • Inability to adhere to any of the protocol guidelines (i.e. alcohol, caffeine consumption)
  • Regular tobacco use
  • Illicit drug use

Outcomes

Primary Outcomes

13CO2 (carbon dioxide) excretion (μmol/kg/h)

Time Frame: 4 hours / study day

Secondary Outcomes

  • 13C-Phenylalanine Oxidation (μmol/kg/h)(4 hours / study day)

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