Evaluation of Protein Requirements in Male Endurance Athletes
Overview
- Phase
- Early Phase 1
- Intervention
- Not specified
- Conditions
- Increased Metabolic Requirement
- Sponsor
- University of Toronto
- Enrollment
- 9
- Primary Endpoint
- 13CO2 (carbon dioxide) excretion (μmol/kg/h)
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).
Nutritional requirements for dietary amino acids in adults have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity.
Recent studies using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 50% higher than RDA based on nitrogen balance data.
Therefore, the purpose of this study is to measure the protein requirement in endurance trained adults using the IAAO technique.
Investigators
Daniel Moore
Assistant Professor
University of Toronto
Eligibility Criteria
Inclusion Criteria
- •Healthy, male, endurance-trained participants who regularly more than 40 km/week
- •Ability to perform the exercise stimulus (20 km run) on metabolic trial.
Exclusion Criteria
- •Inability to meet health and physical activity guidelines according to the physical activity readiness questionnaire (PAR-Q+)
- •Inability to adhere to any of the protocol guidelines (i.e. alcohol, caffeine consumption)
- •Regular tobacco use
- •Illicit drug use
Outcomes
Primary Outcomes
13CO2 (carbon dioxide) excretion (μmol/kg/h)
Time Frame: 4 hours / study day
Secondary Outcomes
- [13C]phenylalanine oxidation (μmol/kg/h)(4 hours/study day)