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临床试验/NCT02478801
NCT02478801已完成早期 1 期

Evaluation of Protein Requirements in Male Endurance Athletes

University of Toronto0 个研究点目标入组 9 人开始时间: 2015年3月最近更新:
适应症

试验速览

阶段
早期 1 期
状态
已完成
入组人数
9
主要终点
13CO2 (carbon dioxide) excretion (μmol/kg/h)

研究概览

简要总结

Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).

Nutritional requirements for dietary amino acids in adults have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity.

Recent studies using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 50% higher than RDA based on nitrogen balance data.

Therefore, the purpose of this study is to measure the protein requirement in endurance trained adults using the IAAO technique.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Healthy, male, endurance-trained participants who regularly more than 40 km/week
  • Ability to perform the exercise stimulus (20 km run) on metabolic trial.

排除标准

  • Inability to meet health and physical activity guidelines according to the physical activity readiness questionnaire (PAR-Q+)
  • Inability to adhere to any of the protocol guidelines (i.e. alcohol, caffeine consumption)
  • Regular tobacco use
  • Illicit drug use

结局指标

主要结局

13CO2 (carbon dioxide) excretion (μmol/kg/h)

时间窗: 4 hours / study day

次要结局

  • [13C]phenylalanine oxidation (μmol/kg/h)(4 hours/study day)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Daniel Moore

Assistant Professor

University of Toronto

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