Efficacy of freeze-dried platelet-rich plasma (FD-PRP) in bone engineering: Pilot study
- Conditions
- alveolar bone atrophy
- Registration Number
- JPRN-UMIN000027144
- Lead Sponsor
- Department of Regenerative Oral Surgely, Nagasaki University Graduate School of Biomediacal Sciences
- Brief Summary
The purpose of this study is to evaluate the safety and preliminary efficacy of autologous freeze-drying platelet-rich plasma (FD-PRP) on maxillary sinus floor bone augmentation as a preliminary pilot study. 5 patients that required sinus floor augmentation to facilitate the placement of dental implants participated in this study. The primary outcome was a safety verification of triple-concentrated FD-PRP (x3 FD-PRP) and there were no adverse events related to the transplantation of FD-PRP.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 5
Not provided
1. All patients are required to be nonsmokers. 2. Patients who have systemic disease, malignances, chronic infections, immune system abnormalities, septicemia, syphilis, HBV, HCV, HTLV-1, HIV, pregnancy, dementia. 3. Patients who have disorder of blood coagulation. 4. Patients who have hepatitis function disorders, metabolic bone disease or skeletal dysplasia. 5. Patients who needs the legal representative.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Safety (including the adverse events)
- Secondary Outcome Measures
Name Time Method