Vitamin D Levels and Survival in Cancer Patients

Completed

• Conditions: Neoplasms

• Registration Number: NCT03266887
• Lead Sponsor: Icelandic Heart Association

Brief Summary

Using the population-based data sources in Iceland and the well-characterized AGES-Reykjavik cohort, our overarching aims are on exploring whether pre-diagnostic serum levels of 25-hydroxyvitamin D (25(OH)D) among older individuals living in Iceland were associated with survival after cancer diagnosis. We also wanted to assess the risk of being diagnosed with cancer in association with 25(OH)D levels. In this population living just south of the arctic circle, vitamin D levels largely depend on dietary- and supplemental sources.

Detailed Description

Not available

Study Timeline

• Study Start: 2002-01-01
• Primary Completion: 2006-12-30
• Study Completion: 2006-12-30
• Status Verified: 2017-08
• Study First Submitted: 2017-08-28
• Study First Submitted QC: 2017-08-28
• Last Update Submitted: 2017-08-28
• Study First Posted: 2017-08-30
• Last Update Posted: 2017-08-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 5764

Inclusion Criteria

To be part of the AGES-Reykjavik Study, initiated between 2002 and 2006.

Exclusion Criteria

Diagnosed with cancer at study entry

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall mortality among cancer patients	Patients were followed from date of diagnosis since 2002 until death or censored at end of the follow-up (December 31, 2014)	We tested the association between pre-diagnostic 25(OH)D levels and total survival

Secondary Outcome Measures

Name	Time	Method
Cancer-specific mortality among cancer patients	Patients were followed from date of diagnosis since 2002 until death or censored at end of the follow-up (December 31, 2014)	We tested the association between pre-diagnostic 25(OH)D levels and cancer survival