Age Gene/Environment Susceptibility Reykjavik Study

Completed

• Conditions: Neoplasms

• Registration Number: NCT03269656
• Lead Sponsor: Icelandic Heart Association

Brief Summary

5764 men and women in Iceland, aged 66 to 96 years entered the Ages Gene/Environment Susceptibility (AGES) - Reykjavik Study. Serum 25(OH)D was measured in 5,519 of all 5,764 (96%) participants at study entry in year 2002 through 2006. The main emphasis was on exploring whether pre-diagnostic serum levels of 25(OH)D were associated with survival after cancer diagnosis.

Detailed Description

Not available

Study Timeline

• Study Start: 2002-01-01
• Primary Completion: 2006-01-31
• Study Completion: 2014-12-31
• Status Verified: 2017-08
• Study First Submitted: 2017-08-30
• Study First Submitted QC: 2017-08-30
• Last Update Submitted: 2017-08-30
• Study First Posted: 2017-09-01
• Last Update Posted: 2017-09-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 5764

Inclusion Criteria

• To participate in the AGES-Reykjavik study

Exclusion Criteria

• To be diagnosed with cancer before study entry

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cancer survival	From date of diagnosis until cancer death or censored at the end of the follow-up (December 31, 2014)	The association between pre-diagnostic 25(OH)D levels in cancer patients and cancer survival
Overall survival	From date of diagnosis until death or censored at end of the follow-up (December 31, 2014)	The association between pre-diagnostic 25(OH)D levels in cancer patients and overall survival

Secondary Outcome Measures

Name	Time	Method
Cancer diagnosis	From date of blood draw (study entry) until cancer diagnosis, death or end of the observation period (December 31, 2014) whichever occurred first	The association between pre-diagnostic 25(OH)D levels and cancer risk