Postoperative nausea and vomiting after general anesthesia with Remimazolam.
- Conditions
- General anesthesia
- Registration Number
- JPRN-jRCT1041210079
- Lead Sponsor
- Suzuki Yuji
- Brief Summary
A retrospective, observational, single-center cohort study comparing the occurrence of postoperative nausea and vomiting with remimazolam and propofol anesthesia was conducted. Bias in anesthetic selection was adjusted for using propensity score matching techniques. A total of 1239 subjects were included and 333 pairs were created. Remimazolam anesthesia was associated with a higher incidence of postoperative nausea and vomiting than propofol anesthesia and was robust after propensity score adjustment.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 4933
All patients who had undergone surgery under general anesthesia at Hamamatsu University Hospital since August 2020.
less than 20 years of age, incorrect enrollment other than general anesthesia, postoperative artificial respiration, cancellation of surgery after induction of anesthesia, lack of consciousness after anesthesia, reoperation within 24 hours after anesthesia, insufficient data due to follow-up shorter than 24 hours, and maintenance with a combination of propofol and remimazolam.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method incidence of postoperative nausea and vomiting
- Secondary Outcome Measures
Name Time Method