Thyroid Hormone Values and Anti-thyroid Peroxidase Antibody Positivity in Recurrent Pregnancy Loss

Completed

• Conditions: Autoimmune Thyroiditis; Recurrent Miscarriage

• Registration Number: NCT05680376
• Lead Sponsor: Zonguldak Bulent Ecevit University

Brief Summary

The aim of this study is to compare the thyroid hormone values and anti-thyroid peroxidase (anti-TPO) levels of women with a diagnosis of recurrent pregnancy loss (RPL) and healthy pregnancies. The primary objective is to find out the relationship between recurrent pregnancy loss with thyroid hormone levels and anti-TPO positivity.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-01
• Primary Completion: 2022-10-01
• Study Completion: 2022-10-01
• Study First Submitted: 2022-11-30
• Status Verified: 2022-12
• Study First Submitted QC: 2022-12-26
• Last Update Submitted: 2022-12-26
• Study First Posted: 2023-01-11
• Last Update Posted: 2023-01-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 103

Inclusion Criteria

• women with 2 or more pregnancy loses
• for controls women with least one healthy baby

Exclusion Criteria

• any other metabolic disease
• women with one miscarriage

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anti-thyroid Peroxidase Antibodies	4 years	presence of Anti-thyroid Peroxidase Antibodies in both groups
Thyroid Hormone Levels	4 years	levels of Thyroid stimulant Hormone, Thyroxin and triiodothyronine levels

Trial Locations

Locations (1)

Zonguldak Bulent Ecevit University Faculty of Medicine; 🇹🇷 Zonguldak, Turkey