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Clinical Trials/NCT05408403
NCT05408403
Completed
N/A

Comparison of the Effects of Transversalis Fascia Plane Block and Anterior QLB ( TFPB and Anterior QLB ) on Postoperative Analgesia in Cesarean Section Surgery

Ondokuz Mayıs University1 site in 1 country49 target enrollmentJune 18, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Analgesia
Sponsor
Ondokuz Mayıs University
Enrollment
49
Locations
1
Primary Endpoint
Opioid consumption in the first 24 hours after surgery
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This study evaluates the postoperative analgesic effects of transversalis fascia plane block and anterior quadratus lumborum block in patients having cesarean section under general anesthesia. General anesthesia will be performed to all patients for the surgery.

Detailed Description

In this study, patients are divided into two groups. After the general anesthesia is performed and cesarean section surgery is over; TFPB block will be performed to patients in Group A ; while anterior QLB block will be performed to patients in Group B. In addition, patient controlled analgesia (PCA) will be used in the first 24 hours postoperatively. Group A - Patients in group A will have TFPB block after the surgery. In addition, patient controlled analgesia (PCA) will be used in the first 24 hours postoperatively. Group B - Patients in group B will have anterior QLB block after the surgery. In addition, patient controlled analgesia (PCA) will be used in the first 24 hours postoperatively.

Registry
clinicaltrials.gov
Start Date
June 18, 2022
End Date
November 8, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Ondokuz Mayıs University
Responsible Party
Principal Investigator
Principal Investigator

SEZGİN BİLGİN

Medical Doctor

Ondokuz Mayıs University

Eligibility Criteria

Inclusion Criteria

  • Being pregnant for at least 37 weeks
  • Planning an elective cesarean operation
  • Being between the ages of 18-45

Exclusion Criteria

  • American Society of Anesthesiologists (ASA) 3-4 patients with comorbidities (Serious renal, cardiac, hepatic disease)
  • Being operated with spinal anesthesia
  • Obesity (\> 100 kg, BMI\> 35 kg / m2)
  • Contraindication of regional anesthesia (coagulopathy, abnormal international normalized ratio (INR), thrombocytopenia, infection at the injection site)
  • Hypersensitivity to local anesthetics or a history of allergy
  • Patients with a history of opioid use longer than four weeks
  • Patients with psychiatric disorders
  • Patients with anatomic deformity
  • Patients who do not want to participate

Outcomes

Primary Outcomes

Opioid consumption in the first 24 hours after surgery

Time Frame: Postoperative Day 1

Morphine consumption in the first 24 hours will be counted by IV patient controlled analgesia device (PCA). Patients will be able to request opioids via PCA device when the nrs score is above 4.

Secondary Outcomes

  • The time of first opioid requirement(Postoperative Day 1)
  • Post-operative acute pain(Postoperative Day 1)

Study Sites (1)

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