Effects of Melatonin on Metabolic Syndrome disease
- Conditions
- metabolic syndrome.Nutritional and metabolic disorders in diseases classified elsewhere
- Registration Number
- IRCT2016111016123N11
- Lead Sponsor
- Vice Chancellor for Research and Technology, Ahvaz Jundishapur University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Age 18 years and older; having at least two of the five metabolic syndrome criteria including waist circumference in men greater than or equal to 102 cm and in women greater than or equal to 88 cm; triglycerides levels (TG) greater than or equal to 150 mg/dL; low-density lipoprotein cholesterol levels (HDL-c) less than or equal to 40 mg/dL in men and less than or equal to 50 mg/dL in women; blood pressure greater than or equal to 130 mmHg or under treatment of Hypertension; fasting blood sugar greater than or equal to 100 mg/dL. b -exclusion criteria: history of alcohol consumption; chronic and acute liver disorders (hepatitis B, C, ...); biliary diseases; autoimmune diseases; cancer; cardiovascular diseases; pulmonary diseases; kidney diseases; pregnancy; breast-feeding; use of contraceptives; hepatotoxic drugs consumption; use of Mineral- multivitamin supplements; weight loss surgery in the recent year; weight loss program in 3 month ago; history of hypothyroidism; Cushing's syndrome.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Triglyceride. Timepoint: before intervention and after 3 months. Method of measurement: serum level.;Total cholesterol. Timepoint: before intervention and after 3 months. Method of measurement: serum level.
- Secondary Outcome Measures
Name Time Method High density lipoprotein (HDL). Timepoint: before intervention and after 3 months. Method of measurement: serum level.;Low density lipoprotein (LDL). Timepoint: before intervention and after 3 months. Method of measurement: serum level.;Leptin. Timepoint: before intervention and after 3 months. Method of measurement: serum level.;Adiponectin. Timepoint: before intervention and after 3 months. Method of measurement: serum level.;Fasting blood sugar. Timepoint: before intervention and after 3 months. Method of measurement: serum level.;Blood pressure. Timepoint: before intervention and after 3 months. Method of measurement: Blood Pressure Monitor.;Waist circumference. Timepoint: before intervention and after 3 months. Method of measurement: Tape measure.;Sleep quality. Timepoint: before intervention and after 3 months. Method of measurement: questionnaire.