NCT00771966已完成4 期
Radical Prostatectomy and Perioperative Fluid Therapy
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- To investigate orthostatic cardiovascular response and orthostatic intolerance in patients after removal of the prostate
研究概览
简要总结
The optimal amount of fluid a patient need under surgery is not clear. Both to much and to little fluid can damage the organ functions.
A strategy called "Goal directed therapy", where the fluid amount a patient need is guided by the stroke volume, has shown to minimize post-operative nausea and vomiting.
The investigators intend to investigate if patients treated after these standards, has a better outcome then patients treated after normal regimes, regarding post-operative orthostatic-intolerance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Patients with cancer in there prostate
排除标准
- •Patients who don't understand the information
- •ASA > III
- •Patients that are under treatment with the drug triazolam
- •Patients with af known renal decease
- •Patients with a psychiatric decease
- •Alcohol abuse
- •Severe haemorrhagic decease
- •Cancer in the mouth,pharynx, larynx or oesophagus
结局指标
主要结局
To investigate orthostatic cardiovascular response and orthostatic intolerance in patients after removal of the prostate
时间窗: 6 hours
次要结局
- Investigate intraoperative haemodynamics(Intraoperative)
研究者
Morten Bundgaard-Nielsen
MD
Rigshospitalet, Denmark
研究点 (1)
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