Radical Prostatectomy and Perioperative Fluid Therapy
Phase 4
Completed
- Conditions
- Prostate Cancer
- Interventions
- Procedure: Maximization of cardiac stroke volume with fluid infusionProcedure: Standard therapy
- Registration Number
- NCT00771966
- Lead Sponsor
- Rigshospitalet, Denmark
- Brief Summary
The optimal amount of fluid a patient need under surgery is not clear. Both to much and to little fluid can damage the organ functions.
A strategy called "Goal directed therapy", where the fluid amount a patient need is guided by the stroke volume, has shown to minimize post-operative nausea and vomiting.
The investigators intend to investigate if patients treated after these standards, has a better outcome then patients treated after normal regimes, regarding post-operative orthostatic-intolerance.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 44
Inclusion Criteria
- Patients with cancer in there prostate
Exclusion Criteria
- Patients who don't understand the information
- ASA > III
- Patients that are under treatment with the drug triazolam
- Patients with af known renal decease
- Patients with a psychiatric decease
- Alcohol abuse
- Severe haemorrhagic decease
- Cancer in the mouth,pharynx, larynx or oesophagus
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description SV maximization Maximization of cardiac stroke volume with fluid infusion - Standard treatment Standard therapy -
- Primary Outcome Measures
Name Time Method To investigate orthostatic cardiovascular response and orthostatic intolerance in patients after removal of the prostate 6 hours
- Secondary Outcome Measures
Name Time Method Investigate intraoperative haemodynamics Intraoperative
Trial Locations
- Locations (1)
Dept of anesthesiology, Rigshospitalet
🇩🇰Copenhagen, Denmark