Influence de la vitesse de perfusion du sérum salé hypertonique/hydroxyethylamidon sur l’hémodynamique systémique au cours du choc septique et hémorragique.

• Conditions: SHOCK HYPOVOLEMIQUE OF SEPTIC OR HAEMORRHAGIC ORIGI

• Registration Number: EUCTR2007-001475-11-FR
• Lead Sponsor: Assistance Publique Hopitaux de marseille

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-05-10
• Last Update Posted: 19 March 2012

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

PATIENTS PRESENTING A HYPOVOLEMIE AIGUE WHITIN THE FRAMEWORK OF A TOXIC SHOCK OR A HAEMORRHAGIC SHOCK
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Patient of less than 18 years
Pregnancy
Absence of assent
Patient at the end of life evolved
Cardiac insufficiency (NYHA III or IV)
Allergy known about the hydroxyethylamidon Hypernatrémie = 150mmol / L

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main Objective: Evaluation of the variation of the Blood pressure Averages according to the speed of drip.;Secondary Objective: ESTIMATE OF THE VARIATION OF the CARDIAC OUTPUT ACCORDING TO THE SPEED OF DRIP OF THE OXYGENATION BY CALCULATION OF the REPORT PAO2/FIO2 <br><br>ESTIMATE OF THE NATREMIE;OF THE CHLOREMIE AND the ARTERIAL PH;Primary end point(s): The tested hypothesis is the absence of significant variations of the average blood pressure hanging and after the administration of HyperHES ® in the group with slow drip (30 minutes) with regard to the values of bases, and the existence of a significant decrease of the average blood pressure hanging in the group receiving HyperHES ® by fast drip (5 minutes) compared with the basic values and with the group with slow drip.