Ascending Aortic Dilation in BiAV After TAVR

• Conditions: Aortic Valve Stenosis
• Interventions: Other: diagnosed as bicuspid aortic valve

• Registration Number: NCT03051334
• Lead Sponsor: Seoul National University Hospital

Brief Summary

This study sought to evaluate changes in ascending aorta size after transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic valve (BiAV) compared with patients with tricuspid aortic valve (TAV).

Detailed Description

The growth rate of ascending aorta was calculated as annual growth rate using baseline and the last echocardiography. The difference in ascending aorta growth rates between the two groups (BiAV and TAV) were analyzed by independent t-test.

Study Timeline

• Study Start: 2007-01-01
• Status Verified: 2017-02
• Study First Submitted: 2017-02-08
• Study First Submitted QC: 2017-02-08
• Last Update Submitted: 2017-02-08
• Study First Posted: 2017-02-13
• Last Update Posted: 2017-02-13
• Primary Completion: 2017-12-30
• Study Completion: 2017-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Severe AS who underwent TAVR

Exclusion Criteria

• ascending aorta more than 50mm

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
BiAV	diagnosed as bicuspid aortic valve	Bicuspid aortic valve

Primary Outcome Measures

Name	Time	Method
changes in dimension of ascending aorta	baseline and 1year after TAVR	the annual growth rate of ascending aorta(mm/year) using echocardiography

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of