Inhaled Sedation Using the Anesthetic-conserving Device ( ANACONDA) in Prehospital Emergency Medecine.

Completed

• Conditions: Deep Sedation; Endotracheal Intubation

• Registration Number: NCT04141267
• Lead Sponsor: University Hospital, Brest

Brief Summary

Achieving the optimal sedation level for patient management is not always possible using our standard intravenous medications in Pre-hospital Emergency medicine. Inhaled sedation is possible with the Anesthetic-conserving device with a standard respirator.

The pharmacodynamics and pharmacokinetics of halogenated agents allow deep sedation quickly after absorption.

The feasibility of inhaled sedation has never been studied in hospital.

Detailed Description

Retrospecive clinical monocentric study with sedated ventilated patients with isoflurane with the AnaConda® system out of hospital.

Study Timeline

• Status Verified: 2019-02
• Study Start: 2019-05-03
• Primary Completion: 2019-06-03
• Study Completion: 2019-06-03
• Study First Submitted: 2019-08-06
• Study First Submitted QC: 2019-10-24
• Last Update Submitted: 2019-10-24
• Study First Posted: 2019-10-28
• Last Update Posted: 2019-10-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Patient sedated by isoflurane with Anesthetic-conserving device in pre-hospital
• Major patient
• not opposed to participating

Exclusion Criteria

• Adults Under legal protection
• patient refusal to participate in study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
depth of sedation	up to 1 day	depth of sedation (measured by the Ramsay Score) 10 minutes from start of the sedation and at stop of pre hospital sedation. The Ramsay score ranges level of sedation from 1(patient anxious ,agitated,restless) to 6 (patient exhibits no response).

Secondary Outcome Measures

Name	Time	Method
hemodynamic tolerance of patients during isoflurane sedation	up to 1day	comparison of medium blood pressure (mmHg) before isoflurane start and 10 minutes from start of the sedation and at stop of pre hospital sedation

Trial Locations

Locations (1)

CHRU de Brest; 🇫🇷 Brest, France