Effect of Low Level Laser Therapy (LLLT) on severity of post burn immature scars: A randomized control study.
Trial Snapshot
- Phase
- Unknown
- Status
- Completed
- Sponsor
- Enrollment
- 45
- Locations
- 1
- Primary Endpoint
- Vancouver Scar Scale (VSS) score of the scar
Study Overview
Brief Summary
Title of the study: Effectof Low Level Laser Therapy (LLLT) on severity of post burn immature scars: A randomizedcontrol study.
Research question: What is the effect of combined therapy (LLLT +conventional therapy) on severity of scars compared to conventional therapyalone among the patients with post burn immature scars?
Research hypothesis: Combined therapy is more effective thanconventional therapy in reducing the severity of scars among the patients withpost burn immature scar.
Introduction:
A. Problem statement: A mature scar is flat, soft and supple withcolor matching with that of the surrounding skin. An immature scar is a red, sometimesitchy or painful and slightly elevated scar in the process of remodeling.Immature scars undergo repeated scar breakdown. This is a major problem in thepost burn patients during rehabilitation phase. Various measuresexist including Low level Laser Therapy (LLLT) to make the immature scarmature. No study has been reported from India on effect of LLLT on post burnimmature scar.
B. Rationale: LLLT is claimed to increase collagen synthesis, decreaseinflammation and has positive impact on scar remodeling. LLLT is one of thestandard and safe treatments for immature scars. It can be utilized to promotefaster maturation of post burn scars.
C. Novelty: Limited clinical studies are available on effect of LLLTon severity of post burn scars.
D. Expected outcome and application: Low Level Laser (LLL) haspositive effect on post burn immature scar is expected. Based on outcome ofthis study role of Low Level Laser Therapy (LLLT) may be established as anadjunct in the management of post burn immature scars. This will be useful inrehabilitation of post burn patients.
Aim and objectives:
Aim: To assessthe effect of LLLT on severity of the scars among the patients with post burnimmature scars.
Primary Objective: To assessefficacy of combined therapy (LLLT + conventional treatment) on severity ofpost burn immature scars in comparison with conventional treatment alone.
SecondaryObjective: To identify theclinical factors associated with the efficacy of LLLT on treatment of post burnimmature scars.
Study Design
- Study Type
- Interventional
- Allocation
- Random Number Table
- Masking
- Outcome Assessor Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Subjects with post burn immature scars (vascular, raised, non pliable or itchy).
Exclusion Criteria
- •Subjects with acute burn wounds (<1month old) Subjects with age <18 years and >60 years Subjects with diabetes/ radiation exposure Scars near eyes Scars >4 square feet area Subjects not willing to participate in the study.
Outcomes
Primary Outcomes
Vancouver Scar Scale (VSS) score of the scar
Time Frame: At the time of enrolment of the scar in the study
Secondary Outcomes
- Vancouver Scar Scale (VSS) score of the scar(After eight weeks of intervention over the scar)