Aggravated airway inflammation: research on genomics and optimal surgical treatment
- Conditions
- 10038737chronic rhinosinusitis with nasal polypsnasal polyps
- Registration Number
- NL-OMON50207
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
- 18-65 years of age
- having chronic rhinosinusitis with nasal polyps with an indication for surgery
- 1 oral corticosteroid course / 3 antibiotic courses in the past 2 years; or
at least 1 previous sinus surgery
Exclusion Criteria
- complications of chronic rhinosinusitis warranting surgery
- indication for or previous extensive surgery (external approaches or draf III)
- bleeding diathesis
- pregnancy / breast feeding
- underlying diseases such as CF, PCD, GPA, eGPA, sarcoidosis, HIV, CVID
- use of immunosuppressive or immunomodulatory medication (biologicals, daily
oral corticosteroids)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method