EUCTR2010-023455-28-FI进行中(未招募)不适用
Dexmedetomidine pharmacokinetics during continuous venovenous hemofiltration and hemodiafiltration in critically ill patients - Dexmedetomidine study
Maija Kaukonen0 个研究点目标入组 10 人开始时间: 2010年11月3日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •1. age = 18
- •2. clinical need for sedation
- •3. acute kidney injury requiring renal replacement therapy (according to ICUs standard operating procedures, one or more of the following criteria)
- •-oliguria (diuresis < 200ml/12h) or anuria
- •-severe acidosis (pH < 7.1-7.2) or rapidly deteriorating acidosis
- •-hyperpotassemia
- •-urea > 30 mmol/l and/or creatinine >500 umol/l or uremic complications (encephalopatia, pericarditis)
- •-significant fluid retention (high IAP, pulmonary oedema, severe peripheral oedema)
- •-rhabdomyolysis
- •-especially the combination of oliguria and deteriorating acidosis and/or hyperpotassemia is an indication for early initiation of renal replacement therapy
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1. Severe bradycardia (HR<50/min)
- •2. AV conduction block II-III (unless pacemaker installed)
- •3. Severe hepatic impairment (bilirubin >101 umol/l)
- •4. Pregnancy or lactation
- •5. Age <18
研究者
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